Minisymposium: Liver Pathobiology: Therapeutics and Pathway Targets

Minisymposium: Liver Pathobiology: Therapeutics and Pathway Targets

Saturday, April 2, 2022 • 2:00 PM - 5:00 PM (EDT)

Pennsylvania Convention Center, Room 115-A


Sharon DeMorrow, PhDChair
Sharon DeMorrow, PhD
University of Texas at Austin

Heather Francis, PhDCo-Chair
Heather Francis, PhD
Richard L. Roudebush VA Medical Center


Session Description: This session will feature 12 abstract-driven short talks

  • Chair - Welcome and Introductions

Presentation Time

Presenting Author

Abstract Title

Abstract Number

2:00 PM - 2:15 PM

Ludovica Ceci

Suppression of MT1 and Melatonin Treatment Improves Liver Phenotypes in Mdr2-/- mice

Abstract R2756

2:15 PM - 2:30 PM

Evan Delgado

Investigating Susceptibility of β-catenin-mutated Hepatocellular Carcinoma to Checkpoint Inhibitors

Abstract R2950

2:30 PM - 2:45 PM

Shikai Hu

Therapeutic implication of SOX9 and YAP1 co-repression in advanced intrahepatic cholangiocarcinoma

Abstract R3050

2:45 PM - 3:00 PM

Anders Ohman

Regulation of Transplanted Fetal Hepatocyte Proliferation by Histone Post-Translational Modifications

Abstract R3218

3:00 PM - 3:15 PM

Valerie Gouon-Evans

Use of Nucleoside Modified mRNA Encoding Regenerative Factors Encapsulated with Lipid Nanoparticles to Alleviate Acute and Chronic Murine Liver Diseases

Abstract R3230

3:15 PM - 3:30 PM

Shikai Hu

A PanFzd receptor agonist induces β-catenin activation to promote hepatic repair after surgical and acetaminophen-induced injury

Abstract R3789

3:30 PM - 3:45 PM

Sharon DeMorrow

Targeting Galanin Receptor Signaling as a Novel Therapeutic Strategy for the Treatment of Fatty Liver Disease

Abstract R4216

3:45 PM - 4:00 PM

Ming-Hsien Chan

Magnetically Guided Theranostics: Enhancing the Contrast of Magnetic Resonance Imaging with Multiple-Layer Montmorillonite-Based Iron/Platinum Nanoparticles for the Treatment of Orthotopic Hepatocellular Carcinoma

Abstract R4347

4:00 PM - 4:15 PM

Shikai Hu

Enabling regeneration in a β-catenin-deficient liver: Unraveling a novel compensatory role of mTOR

Abstract R4546

4:15 PM - 4:30 PM

Jennifer Truong

Inhibition of Ileal Bile Acid Transport is Protective Against Cholestatic Liver Injury in Cyp2c70-/-Mice with Humanized Bile Acid Composition

Abstract R5088

4:30 PM - 4:45 PM

Evan Delgado

Understanding Molecular Heterogeneity in Hepatocellular Carcinoma

Abstract R5218

4:45 PM - 5:00 PM

Narendra Kumar

Role of Jak3 in cross talk between Intestinal and biliary epithelial cells

Abstract R5653